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Cold Sores  What are cold sores?Cold sores are caused by a viral infection that attacks the skin and nervous system. They are small, painful, fluid-filled blisters on the mouth or nose. Cold Sores are a common condition. Some estimates indicate that over 80% of the population will suffer from a cold sore (herpes simplex 1) sometime in their life.What causes cold sores?Cold sores are caused by the virus known as herpes simplex type I (HSV-1). After the first episode of the disease, the virus lies dormant in the nerves or skin around the original area until something sets the virus off into another eruption. Colds, flu, and even stress can cause you to have an outbreak of cold sores. Why you have an outbreak at one time of life and not another is not clearly understood.HSV-1 is different from herpes simplex type II (HSV-2), which is the virus that causes the sexually transmitted disease known as genital herpes. HSV-1 is a very common virus. It is thought that 80% of adults have been exposed to the virus during their lifetime. You may not develop cold sores when you are first infected with HSV. If cold sores do develop when you are first infected, they may be more severe than in later outbreaks. During the first outbreak of cold sores, the blisters may spread to any part of the mouth. Recurrent cold soresOnce infected, the HSV virus from cold sores remains in your body and may cause cold sores to return throughout your lifetime (recurrent cold sores). Most people have 3 to 4 outbreaks per year, although a few people have more than one cold sore attack per month.Recurrent cold sores usually develop where facial skin and the lip meet. About 6 to 48 hours before a cold sore is visible, you may feel tingling, burning, itching, numbness, tenderness, or pain in the affected area. This is called the prodromal stage. L-Lysine supplements along with a topical treatment can help lessen and stop outbreaks. Learn More about Cold Sores
Cold Sores Testimonials
Cold Sores Medical Studies Cold SoresHerpes Labialis (Cold Sores) & Extract (Lo-701) for topical treatment of recurring herpes labialis.Koytchev R, Alken RG, Dundarov S.Cooperative Clinical Drug Research and Development GmbH, Berlin, Germany. ccdrd@drug-news.com A double-blind, placebo-controlled, randomized trial was carried out with the aim of proving efficacy of standardized balm mint cream [active ingredient: 1% Lo-701--extract from Melissa officinalis (70:1)] for the therapy of herpes simplex labialis. Sixty six patients with a history of recurrent herpes labialis (at least four episodes per year) in one center were treated topically; 34 of them with verum and 32 with placebo. The cream had to be smeared on the affected area four times daily over five days. A combined symptom score of the values for complaints, size of affected area and blisters at day 2 of therapy was formed as the primary target parameter. There was a significant difference in the values of the primary target parameter between both treatment groups: verum 4.03 +/- 0.33 (3.0); placebo 4.94 +/- 0.40 (5.0); values given are mean +/- SEM (median) of the symptoms score on day 2 of therapy. The tested formulation is effective for the treatment of herpes simplex labialis. The significant difference in the combined symptom score on the second day of treatment is of particular importance having in mind that the complaints in patients suffering from herpes labialis are usually most intensive at that time. In addition to the shortening of the healing period, the prevention of a spreading of the infection and the rapid effect on typical symptoms of herpes like itching, tingling, burning, stabbing, swelling, tautness and erythema, the balm mint cream has a further advantage. The different mechanism of action of the extract rules out the development of resistance of the herpes virus. Some indication exists that the intervals between the periods with herpes might be prolonged with melissa. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 10589440 [PubMed - indexed for MEDLINE] »view more medical studies
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