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Genital Herpes  What is genital herpes?Genital herpes is a common, highly infectious disease that infects the nerve cells at the base of the spinal column. It is transmitted from one person to another during sexual activity. Genital herpes causes blisters or groups of small ulcers on and around the genitals in both men and women.Genital herpes is extremely widespread, largely because it is so contagious. Carriers can transmit the disease without having any symptoms themselves of active infection. As many as 50 million Americans are infected with genital herpes, with 1 million new infections each year. As many as 80-90% of those infected fail to recognize herpes symptoms or have no symptoms at all. The highest rates of infection are seen among the poor, those with less education, those using cocaine, and those with many sexual partners. Transmitting genital herpesThe herpes virus is highly contagious. Anyone experiencing symptoms of a herpetic lesion must be very cautious when being intimate with another person. If the virus has been transmitted, the infection is permanent. Recent studies indicate that some people (perhaps 10% of those infected with herpes) may be contagious at any time even without visible signs of an outbreak. This symptom is called viral shedding. Anyone having herpes should always be cautious to not transmit the disease, even when an outbreak is not present.Genital herpes cannot be cured, only controlled. Learn More about Genital Herpes Genital Herpes Testimonials
Genital Herpes Medical Studies Genital Herpes (HSV2)Antiviral activity of Melissa officinalis and other plant extracts against Herpes simplex virus type-2.Allahverdiyev A, Duran N, Ozguven M, Koltas S.Tropical Diseases Center, Faculty of Medicine, Cukurova University, Adana, Turkey. Melissa officinalis L. (Lamiaceae)and other plant extracts have been used in a variety of practical applications in medical science. Our objective in the current study was to determine the effects of the volatile oil components of M. officinalis on Herpes simplex virus type 2 (HSV-2) replication in HEp-2 cells. Four different concentrations (25, 50, 100, 150 and 200 microg/ml) of volatile oils were examined. Experiments were carried out using HEp-2 cells. M. officinalis volatile oil was found to be non-toxic to HEp-2 cells up to a concentration of 100 micro/ml. It was, however, found to be slightly toxic at a concentration over of 100 microg/ml. The antiviral activity of non-toxic concentrations against HSV-2 was tested. The replication of HSV-1, and HSV-2 was inhibited, indicating that the M. officinalis and other plant extracts contain anti-HSV-2 substances. PMID: 15636181 [PubMed - indexed for MEDLINE] Antiviral activity of Australian Melaleuca alternifolia and eucalyptol plant extracts against herpes simplex virus in cell culture.Schnitzler P, Schon K, Reichling J.Department of Virology, Hygiene Institute, University of Heidelberg, Germany. The antiviral effect of Melaleuca alterfernolia (TTO) and eucalyptol (EUO) and other plant extracts against herpes simplex virus was examined. Cytotoxicity of TTO and EUO was evaluated in a standard neutral red dye uptake assay. Toxicity of TTO and EUO was moderate for RC-37 cells and approached 50% (TC50) at concentrations of 0.006% and 0.03%, respectively. Antiviral activity of TTO and EUO against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) was tested in vitro on RC-37 cells using a plaque reduction assay. The 50% inhibitory concentration (IC50) of TTO for herpes simplex virus plaque formation was 0.0009% and 0.0008% and the IC50 of EUO was determined at 0.009% and 0.008% for HSV-1 and HSV-2, respectively. Australian tea tree oil exhibited high levels of virucidal activity against HSV-1 and HSV-2 in viral suspension tests. At noncytotoxic concentrations of TTO plaque formation was reduced by 98.2% and 93.0% for HSV-1 and HSV-2, respectively. Noncytotoxic concentrations of EUO reduced virus titers by 57.9% for HSV-1 and 75.4% for HSV-2. Virus titers were reduced significantly with TTO, whereas EUO exhibited distinct but less antiviral activity. In order to determine the mode of antiviral action of both essential oils, either cells were pretreated before viral infection or viruses were incubated with TTO or EUO before infection, during adsorption or after penetration into the host cells. Plaque formation was clearly reduced, when herpes simplex virus was pretreated with the essential oils prior to adsorption. These results indicate that TTO and EUO affect the virus before or during adsorption, but not after penetration into the host cell. Thus TTO and EUO are capable to exert a direct antiviral effect on HSV. Although the active antiherpes components of Australian tea tree and eucalyptus oil are not yet known, their possible application as antiviral agents in recurrent herpes infection is promising. PMID: 11338678 [PubMed - indexed for MEDLINE] PMID: 6423612 [PubMed - indexed for MEDLINE] Subjective Response to Lysine in the Therapy of Herpes Simplex.Walsh DE, Griffith RS, Behforooz A.To test the effect of lysine supplementation on herpes infection, 1543 subjects were surveyed by questionnaire after a six-month trial period. The study included subjects with cold sores, canker sores, and genital herpes. Of these, 54% had been diagnosed and treated by a physician. The results showed that the average dosage used was 936 mg of lysine daily. Eighty-four per cent of those surveyed said that lysine supplementation prevented recurrence or decreased the frequency of herpes infection. Whereas 79% described their symptoms as severe or intolerable without lysine, only 8% used these terms when taking lysine. Without lysine, 90% indicated that healing took six to 15 days, but with lysine 83% stated that lesions healed in five days or less. Overall, 88% considered supplemental lysine an effective form of treatment for herpes infection. PMID: 6423612 [PubMed - indexed for MEDLINE] »view more medical studies
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