Uncovering the Root of Skin Tags

Alana Korol

Common Health Conditions That May Cause Skin Tags

For something so familiar, skin tags are relatively unknown to the medical community. These fleshy growths can appear in almost any location throughout the body. While most cases are found in older adults, they may be present in people of all ages, genders, and nationalities. Officially defined as an accumulation of collagen fibers, blood vessels, and skin cells, these growths are more of a nuisance than an actual cause of concern. Although many risk factors are associated with the growth and progression of skin tags, preliminary evidence suggests certain medical conditions can encourage the development of these pesky skin lesions.

The Connection Between Obesity and Skin Tags

Almost every system within your body is negatively affected as you begin to gain excess fat. When the human body progresses from just a few pounds overweight into the realm of obesity, the dangers associated with the rise in body fat extend to your internal health and your external appearance. According to the journal Clinics in Dermatology, obesity directly influences skin conditions known as dermatoses. Along with everyday issues, such as stretch marks, obesity alters nerve endings within your skin and even the way blood travels throughout the skin. Along with an increase in various medical conditions, there seems to be a direct connection between obesity and skin tags.

Although the epidemiological evidence linking obesity and skin tags is inconclusive, physicians believe the friction caused by excessive skin folds and creases promotes the formation of skin tags. There may be a connection between obesity, hormonal alterations, and the progression of skin tags. Still, there is not enough evidence to link this potential cause fully.

The Diabetes Link – Insulin Resistance and Skin Tags

Diabetes causes a myriad of issues within the human body. However, one of the more surprising discoveries is the link between diabetes and skin tags. According to a study outlined by the Europe PubMed Central medical journal database, researchers found that out of 216 cases of skin tags, roughly 30 percent of patients featured skin tags. Along with the presence of diabetes, nearly 28 percent of these skin tag cases were among those who were classified as obese. Although there was not enough evidence to fully suggest a connection between obese patients and skin tags (within this particular study), significant evidence indicated that those unable to metabolize carbohydrates were at a greater risk of developing skin tags. Preliminary studies may suggest that the severity of skin tags may be an excellent indicator for those at an increased risk of developing diabetes.

Moreover, another study published in the Journal of Clinical Pathology found a direct connection between the development of skin tags and not only Type 2 diabetes but also cardiovascular disease. Therefore, the interaction between blood sugar and circulating blood fats may play a direct role in forming these benign skin growths.

HPV and Skin Tags – A Potential for Growth

HPV, or the human papillomavirus, is found in various forms. While some versions of the HPV virus afflict specific body portions, such as the feet or genitals, others may showcase themselves in unusual fleshy growths, such as skin tags. According to the information outlined by the Indian Journal of Dermatology, Venereology, and Leprology, All India Institute of Medical Sciences researchers found the HPV-6 and HPV-11 virus DNA within 48.6 percent of evaluated skin tags. This is an exciting development as it suggests some skin tags may result from a viral infection. Although HPV-6 and HPV-11 are considered "low-risk" versions of the virus, some skin tags may develop due to viral transmission on some level.

Another general study outlined by the British Journal of Dermatology found concentrations of the HPV6/11 virus within skin tags. Researchers evaluated skin tags from 49 patients throughout the study. The extracted skin tags were tested using a unique analysis designed to identify all forms of the HPV virus. At the end of the study, roughly 88 percent of skin tags revealed concentrations of HPV-6 and HPV-11. These results support the theory that some forms of skin tags directly result from an HPV viral infection.

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